Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
neural precursor cell expressed developmentally down-regulated protein 4
KIAA0093 RPF1 |
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:cancer
neurodegenerative diseases |
| gptkbp:discoveredBy |
Harvey F. Lodish
|
| gptkbp:encodes |
NEDD4 protein
|
| gptkbp:Entrez_Gene_ID |
4734
ENSG00000133119 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:firstDescribed |
1992
|
| gptkbp:function |
E3 ubiquitin-protein ligase activity
|
| gptkbp:HGNC_ID |
7727
|
| https://www.w3.org/2000/01/rdf-schema#label |
NEDD4 gene
|
| gptkbp:involvedIn |
signal transduction
regulation of cell growth protein ubiquitination |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_15
|
| gptkbp:OMIM |
602278
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Nedd4
|
| gptkbp:proteinFamily |
gptkb:WW_domain
gptkb:HECT_domain C2 domain |
| gptkbp:regulates |
gptkb:PTEN_protein
ENaC (epithelial sodium channel) |
| gptkbp:UniProtID |
P46934
|
| gptkbp:bfsParent |
gptkb:NEDD4-1
|
| gptkbp:bfsLayer |
6
|