|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:Mitogen-activated_protein_kinase_p38_beta
gptkb:PRKM11
gptkb:SAPK2b
gptkb:p38beta
|
|
gptkbp:associatedWith
|
inflammatory diseases
cancer (various types)
|
|
gptkbp:biologicalProcess
|
ATP binding
protein serine/threonine kinase activity
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:discoveredBy
|
1996
|
|
gptkbp:encodes
|
gptkb:p38_beta
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000185386
5600
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:foundIn
|
human genome
|
|
gptkbp:fullName
|
gptkb:Mitogen-activated_protein_kinase_11
|
|
gptkbp:function
|
signal transduction
regulation of gene expression
inflammatory response
cellular response to stress
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:has_protein_product
|
NP_002742
|
|
gptkbp:has_transcript
|
gptkb:NM_002751
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:6871
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAPK11
|
|
gptkbp:involves
|
gptkb:MAPK_signaling_pathway
stress-activated protein kinase signaling cascade
|
|
gptkbp:locatedOnChromosome
|
22
|
|
gptkbp:location
|
gptkb:22q13.33
|
|
gptkbp:memberOf
|
gptkb:MAP_kinase_family
gptkb:p38_MAP_kinase_subfamily
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Mapk11
|
|
gptkbp:phosphorylates
|
gptkb:ATF2
gptkb:ELK1
gptkb:MAPKAPK2
gptkb:STAT1
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
cell proliferation
cytokine production
|
|
gptkbp:relatedTo
|
gptkb:MAPK12
gptkb:MAPK13
gptkb:MAPK14
|
|
gptkbp:UniProtID
|
gptkb:Q15759
|
|
gptkbp:bfsParent
|
gptkb:p38_MAPK_pathway
|
|
gptkbp:bfsLayer
|
6
|