Mitogen-activated protein kinase kinase 6
GPTKB entity
Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
gptkb:MKK6
gptkb:MEK6 gptkb:PRKMK6 |
| gptkbp:associatedWith |
apoptosis
cell differentiation immune response |
| gptkbp:biologicalProcess |
inflammatory response
protein kinase activity cellular response to stress |
| gptkbp:Entrez_Gene_ID |
5608
|
| gptkbp:enzymeCommissionNumber |
2.7.12.2
|
| gptkbp:expressedIn |
various human tissues
|
| gptkbp:function |
phosphorylates and activates p38 MAP kinase
|
| gptkbp:gene |
gptkb:MAP2K6
|
| https://www.w3.org/2000/01/rdf-schema#label |
Mitogen-activated protein kinase kinase 6
|
| gptkbp:involves |
gptkb:MAPK_signaling_pathway
|
| gptkbp:locatedIn |
gptkb:Homo_sapiens
|
| gptkbp:locatedOnChromosome |
17q24.3
|
| gptkbp:OMIM |
602425
|
| gptkbp:RefSeq |
NP_002749.1
|
| gptkbp:regulates |
activated by phosphorylation
activated by MAP3K proteins |
| gptkbp:substrate |
gptkb:MAPK11
gptkb:MAPK12 gptkb:MAPK13 gptkb:MAPK14 |
| gptkbp:UniProtID |
gptkb:P52564
|
| gptkbp:bfsParent |
gptkb:MAP2K6
gptkb:MKK6 |
| gptkbp:bfsLayer |
7
|