|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:p38_gamma
gptkb:ERK6
gptkb:SAPK3
|
|
gptkbp:encodedBy
|
gptkb:MAPK12_gene
|
|
gptkbp:Entrez_Gene_ID
|
6300
ENSG00000188130
|
|
gptkbp:enzymeClassification
|
gptkb:EC_2.7.11.24
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
heart
|
|
gptkbp:family
|
gptkb:MAP_kinase_family
|
|
gptkbp:fullName
|
gptkb:Mitogen-activated_protein_kinase_12
|
|
gptkbp:function
|
signal transduction
regulation of gene expression
cellular response to stress
|
|
gptkbp:GO_term
|
GO:0004672 (protein kinase activity)
GO:0005524 (ATP binding)
GO:0000165 (MAPK cascade)
|
|
gptkbp:HGNC_ID
|
HGNC:6872
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAPK12
|
|
gptkbp:involvedIn
|
apoptosis
inflammatory response
myogenesis
|
|
gptkbp:locatedOnChromosome
|
chromosome 22
|
|
gptkbp:location
|
gptkb:22q13.33
|
|
gptkbp:molecularWeight
|
42 kDa
|
|
gptkbp:OMIM
|
602399
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Mapk12
|
|
gptkbp:PDB
|
3E7O
3E7P
3E7Q
3E7R
3E7S
3E7T
3E7U
3E7V
3E7W
3E7X
3E7Y
3E7Z
3GC8
|
|
gptkbp:phosphorylates
|
transcription factors
Thr183
Tyr185
|
|
gptkbp:RefSeq
|
NM_002969
|
|
gptkbp:relatedTo
|
gptkb:MAPK11
gptkb:MAPK13
gptkb:MAPK14
|
|
gptkbp:subfamily
|
gptkb:p38_MAP_kinase_subfamily
|
|
gptkbp:UniProtID
|
O15264
|
|
gptkbp:bfsParent
|
gptkb:p38_MAPK_pathway
|
|
gptkbp:bfsLayer
|
6
|