|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:p38_beta
gptkb:SAPK4
CSBP2
PRKM14
|
|
gptkbp:associatedWith
|
gptkb:cancer
autoimmune diseases
inflammatory diseases
|
|
gptkbp:biologicalProcess
|
ATP binding
apoptotic process
inflammatory response
protein kinase activity
cellular response to stress
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:discoveredBy
|
1996
|
|
gptkbp:Entrez_Gene_ID
|
1437
ENSG00000112062
|
|
gptkbp:expressedIn
|
many tissues
immune cells
|
|
gptkbp:fullName
|
Mitogen-activated protein kinase-activated protein kinase 14
|
|
gptkbp:function
|
serine/threonine-protein kinase
regulates transcription in response to stress
involved in stress-activated protein kinase signaling cascade
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:MAPKAPK14
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAPKAPK14
|
|
gptkbp:inhibitedBy
|
gptkb:SB203580
gptkb:BIRB_796
gptkb:VX-702
|
|
gptkbp:length
|
365
|
|
gptkbp:locatedOnChromosome
|
gptkb:6p21.31
|
|
gptkbp:molecularWeight
|
41 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Mapkapk14
rat Mapkapk14
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:p38_MAPK_pathway
|
|
gptkbp:PDB
|
3PY3
1A9U
|
|
gptkbp:phosphorylates
|
gptkb:ATF2
gptkb:MAPKAPK2
gptkb:MAPKAPK3
gptkb:STAT1
gptkb:MAPT
gptkb:HSPB1
|
|
gptkbp:regulates
|
activated by dual phosphorylation on Thr and Tyr
|
|
gptkbp:UniProtID
|
gptkb:Q16539
|
|
gptkbp:upstream_activator
|
gptkb:MKK3
gptkb:MKK6
|
|
gptkbp:bfsParent
|
gptkb:RAF1_gene
|
|
gptkbp:bfsLayer
|
7
|