MAPKAPK3

URI: https://gptkb.org/entity/MAPKAPK3

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:gene
gptkbp:alias	gptkb:3pK gptkb:MAPK-activated_protein_kinase_3 gptkb:MAPKAP_kinase_3
gptkbp:alternativeSplicing	yes
gptkbp:associatedWith	gptkb:cancer
gptkbp:discoveredBy	1996
gptkbp:Entrez_Gene_ID	gptkb:ENSG00000111206 7867
gptkbp:expressedIn	various tissues
gptkbp:fullName	gptkb:Mitogen-activated_protein_kinase-activated_protein_kinase_3
gptkbp:function	signal transduction serine/threonine kinase activity
gptkbp:GO_term	gptkb:GO:0004674 GO:0005524 GO:0000165
gptkbp:HGNC_ID	gptkb:MAPKAPK3
https://www.w3.org/2000/01/rdf-schema#label	MAPKAPK3
gptkbp:interactsWith	gptkb:MAPK1 gptkb:ATF2 gptkb:HSP27 gptkb:MAPK14 gptkb:CREB-binding_protein
gptkbp:locatedOnChromosome	3p21.31 chromosome 3: 47,054,282-47,073,222 (GRCh38)
gptkbp:molecularWeight	43 kDa
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:orthologInMouse	gptkb:Mapkapk3
gptkbp:pathway	gptkb:MAPK_signaling_pathway
gptkbp:PDB	gptkb:2OZA 2OZB
gptkbp:phosphorylates	gptkb:ATF2 gptkb:HSP27 gptkb:CREB-binding_protein gptkb:ERK gptkb:p38_MAP_kinase
gptkbp:proteinFamily	gptkb:MAPKAP_kinase_family
gptkbp:relatedTo	cell differentiation cell proliferation inflammation stress response
gptkbp:subcellularLocation	gptkb:nucleus gptkb:cytoplasm
gptkbp:substrate	gptkb:MAPK1 gptkb:MAPK14
gptkbp:UniProtID	gptkb:P46734
gptkbp:bfsParent	gptkb:p38_MAPK_pathway
gptkbp:bfsLayer	6