|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:BTEB3
gptkb:EZF
gptkb:GKLF
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:glioblastoma
colorectal cancer
skin diseases
|
|
gptkbp:discoveredBy
|
gptkb:Yoshinori_Nagai
|
|
gptkbp:discoveredIn
|
1996
|
|
gptkbp:encodedBy
|
gptkb:KLF4_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000136826
9314
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skin
cornea
colon
epithelial cells
|
|
gptkbp:fullName
|
gptkb:Kruppel-like_factor_4
|
|
gptkbp:function
|
regulation of apoptosis
regulation of cell proliferation
transcription factor
regulation of differentiation
maintenance of stem cell pluripotency
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:6348
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Klf4
|
|
gptkbp:interactsWith
|
gptkb:Sox2
gptkb:c-Myc
gptkb:Oct4
|
|
gptkbp:locatedOnChromosome
|
9q31
|
|
gptkbp:molecularWeight
|
55 kDa
|
|
gptkbp:OMIM
|
602253
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:2WBU
|
|
gptkbp:regulates
|
gptkb:p21
gptkb:E-cadherin
gptkb:Kruppel-like_factors
gptkb:Nanog
differentiation
inflammation
cell cycle
cellular reprogramming
DNA damage response
epithelial-mesenchymal transition
|
|
gptkbp:role
|
induced pluripotent stem cells
|
|
gptkbp:UniProtID
|
O43474
|
|
gptkbp:YamanakaFactor
|
true
|
|
gptkbp:zincFingerDomains
|
3
|
|
gptkbp:bfsParent
|
gptkb:The_Reprogramming_of_Differentiated_Cells
|
|
gptkbp:bfsLayer
|
5
|