|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:EZF
gptkb:GKLF
|
|
gptkbp:associatedWith
|
gptkb:cancer
colorectal cancer
skin diseases
|
|
gptkbp:discoveredBy
|
gptkb:Yoshinori_Nagai
|
|
gptkbp:discoveredIn
|
1996
|
|
gptkbp:encodes
|
gptkb:Kruppel-like_factor_4_protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000136826
9314
|
|
gptkbp:expressedIn
|
gptkb:skin
cornea
intestine
epithelial tissues
|
|
gptkbp:fullName
|
gptkb:Kruppel-like_factor_4
|
|
gptkbp:function
|
regulation of apoptosis
regulation of cell proliferation
transcription factor
regulation of differentiation
maintenance of stem cell pluripotency
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:6348
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
KLF4 gene
|
|
gptkbp:locatedOnChromosome
|
gptkb:9q31.2
9
|
|
gptkbp:memberOf
|
gptkb:Kruppel-like_factor_family
|
|
gptkbp:OMIM
|
602253
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Klf4
|
|
gptkbp:regulates
|
gptkb:p21_(CDKN1A)
wound healing
angiogenesis
inflammation
cell cycle
cellular reprogramming
tumor suppression
oncogenesis
epithelial-mesenchymal transition
stem cell self-renewal
barrier function in skin
differentiation of goblet cells
|
|
gptkbp:symbol
|
gptkb:KLF4
|
|
gptkbp:transcriptional_activity
|
activator
repressor
|
|
gptkbp:UniProtID
|
O43474
|
|
gptkbp:usedIn
|
induced pluripotent stem cell generation
|
|
gptkbp:Yamanaka_factor
|
true
|
|
gptkbp:bfsParent
|
gptkb:Klf4
|
|
gptkbp:bfsLayer
|
6
|