Statements (63)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:DNA
|
| gptkbp:associated_with |
Stem cells
|
| gptkbp:function |
Regulates pluripotency
|
| gptkbp:has_role |
Cell differentiation
Development |
| https://www.w3.org/2000/01/rdf-schema#label |
Sox2
|
| gptkbp:interacts_with |
gptkb:Oct4
gptkb:Nanog |
| gptkbp:involved_in |
Neurogenesis
|
| gptkbp:is_associated_with |
Neurodegenerative diseases
Tumorigenesis |
| gptkbp:is_essential_for |
Maintaining pluripotency
|
| gptkbp:is_expressed_in |
gptkb:disease
gptkb:Brain gptkb:Heart gptkb:Lung Embryonic stem cells Pancreas Liver Intestine Germ cells Ovary Neural stem cells Spinal cord Testis |
| gptkbp:is_involved_in |
gptkb:Oncology
Apoptosis Embryonic development Immune response Metabolism Cell cycle regulation Transcriptional regulation Cell migration Cellular proliferation DNA repair Signal transduction Cellular stress response Organogenesis Cellular signaling pathways Chromatin remodeling Cell adhesion Protein-protein interactions Cellular homeostasis Tissue repair Cellular differentiation Cellular aging Post-transcriptional regulation Cellular apoptosis Cell reprogramming |
| gptkbp:is_part_of |
Sox family
|
| gptkbp:is_regulated_by |
BMP
FGF LIF |
| gptkbp:is_studied_in |
Regenerative medicine
Developmental biology Stem cell research |
| gptkbp:located_in |
gptkb:Atom
|
| gptkbp:orthologs |
gptkb:mouse
gptkb:Fruit_fly gptkb:Zebrafish |
| gptkbp:regulates |
Gene expression
|
| gptkbp:bfsParent |
gptkb:Yamanaka_factors
|
| gptkbp:bfsLayer |
4
|