|
gptkbp:instanceOf
|
gptkb:transcription_factor
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Oct3/4
gptkb:POU5F1
gptkb:POU_domain,_class_5,_transcription_factor_1
Oct-3
Oct-3/4
|
|
gptkbp:binds
|
octamer motif (ATGCAAAT)
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:encodedBy
|
gptkb:POU5F1_gene
|
|
gptkbp:expressedIn
|
gptkb:germ_cells
embryonic stem cells
|
|
gptkbp:foundIn
|
humans
mammals
|
|
gptkbp:function
|
maintenance of stem cell self-renewal
regulation of pluripotency
|
|
gptkbp:HGNC_ID
|
9221
|
|
gptkbp:interactsWith
|
gptkb:Klf4
gptkb:Sox2
gptkb:c-Myc
gptkb:Nanog
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6p21.31
|
|
gptkbp:memberOf
|
gptkb:POU_family
|
|
gptkbp:molecularWeight
|
38 kDa
|
|
gptkbp:OMIM
|
164177
|
|
gptkbp:regulates
|
gene expression
|
|
gptkbp:requires
|
early embryonic development
|
|
gptkbp:structure
|
contains POU-specific and POU-homeodomain
|
|
gptkbp:UniProtID
|
gptkb:Q01860
|
|
gptkbp:usedIn
|
induced pluripotent stem cell generation
|
|
gptkbp:bfsParent
|
gptkb:Klf4
gptkb:Sox2
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Oct4
|