|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:Homeobox_protein_NANOG
|
|
gptkbp:discoveredBy
|
gptkb:Austin_Smith
|
|
gptkbp:discoveredIn
|
2003
|
|
gptkbp:encodedBy
|
gptkb:NANOG_gene
|
|
gptkbp:Entrez_Gene_ID
|
79923
|
|
gptkbp:expressedIn
|
embryonic stem cells
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:HGNC_ID
|
20857
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Nanog
|
|
gptkbp:interactsWith
|
gptkb:KLF4
gptkb:OCT4
gptkb:SOX2
|
|
gptkbp:involvedIn
|
stem cell biology
reprogramming somatic cells
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_12
|
|
gptkbp:mutationAssociatedWith
|
loss of pluripotency
|
|
gptkbp:namedAfter
|
Tír na nÓg (mythological land of youth)
|
|
gptkbp:OMIM
|
607937
|
|
gptkbp:orthologIn
|
gptkb:mouse_Nanog
|
|
gptkbp:regulates
|
cell differentiation
pluripotency genes
regulated by TGF-beta signaling
regulated by OCT4
regulated by SOX2
|
|
gptkbp:role
|
maintenance of pluripotency
self-renewal of embryonic stem cells
|
|
gptkbp:sequence
|
homeobox domain
|
|
gptkbp:structure
|
contains homeodomain
|
|
gptkbp:UniProtID
|
Q9H9S0
|
|
gptkbp:bfsParent
|
gptkb:Klf4
gptkb:Oct3/4
gptkb:Sox2
|
|
gptkbp:bfsLayer
|
6
|