|
gptkbp:instanceOf
|
gptkb:Ensembl_gene_ID
|
|
gptkbp:alias
|
gptkb:ERBB
gptkb:ERBB1
gptkb:HER1
mENA
|
|
gptkbp:approvedBy
|
gptkb:epidermal_growth_factor_receptor
|
|
gptkbp:approvedSymbol
|
gptkb:EGFR
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:glioblastoma
gptkb:non-small_cell_lung_carcinoma
colorectal cancer
|
|
gptkbp:chromosomeArm
|
p
|
|
gptkbp:discoveredIn
|
1984
|
|
gptkbp:domain
|
transmembrane domain
extracellular ligand-binding domain
tyrosine kinase domain
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000146648
1956
|
|
gptkbp:function
|
gptkb:receptor_tyrosine_kinase
|
|
gptkbp:gene
|
gptkb:EGFR
gptkb:epidermal_growth_factor_receptor
|
|
gptkbp:HGNC_ID
|
HGNC:3467
|
|
gptkbp:isCancerGene
|
true
|
|
gptkbp:isOncogene
|
true
|
|
gptkbp:locatedOnChromosome
|
gptkb:7p11.2
7
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:locusType
|
gptkb:gene
|
|
gptkbp:OMIM
|
131550
|
|
gptkbp:orthologInMouse
|
Egfr
|
|
gptkbp:partOf
|
gptkb:ErbB_signaling_pathway
|
|
gptkbp:previousSymbols
|
gptkb:ERBB
gptkb:ERBB1
|
|
gptkbp:proteinFamily
|
protein tyrosine kinase
ErbB receptor family
|
|
gptkbp:refersTo
|
gptkb:EGFR
|
|
gptkbp:RefSeq
|
NM_005228
|
|
gptkbp:reviewedBy
|
gptkb:GeneCards
gptkb:NCBI_Gene
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:target
|
gptkb:afatinib
gptkb:cetuximab
gptkb:erlotinib
gptkb:gefitinib
gptkb:osimertinib
|
|
gptkbp:targetOfDrug
|
true
|
|
gptkbp:UniProtID
|
gptkb:P00533
|
|
gptkbp:bfsParent
|
gptkb:FBgn0001624
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HGNC: 3467
|