GRB2 adaptor protein

URI: https://gptkb.org/entity/GRB2_adaptor_protein

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:Grb-2 gptkb:Growth_factor_receptor-bound_protein_2 gptkb:ASH Protein Ash
gptkbp:domain	SH2 domain SH3 domain
gptkbp:encodedBy	gptkb:GRB2_gene
gptkbp:Entrez_Gene_ID	gptkb:ENSG00000177885
gptkbp:foundIn	gptkb:Homo_sapiens
gptkbp:function	signal transduction adaptor protein
gptkbp:gene	gptkb:GRB2
gptkbp:HGNC_ID	4566
https://www.w3.org/2000/01/rdf-schema#label	GRB2 adaptor protein
gptkbp:interactsWith	gptkb:BCR-ABL gptkb:EGFR gptkb:SHC1 gptkb:SOS1
gptkbp:involves	gptkb:RAS_signaling_pathway gptkb:MAPK_signaling_pathway
gptkbp:locatedOnChromosome	gptkb:17q25
gptkbp:molecularWeight	~25 kDa
gptkbp:OMIM	108355
gptkbp:orthologInMouse	gptkb:Grb2
gptkbp:PDB	gptkb:1GRI
gptkbp:RefSeq	NP_002078.2
gptkbp:subcellularLocation	gptkb:cytoplasm gptkb:plasma_membrane
gptkbp:UniProtID	gptkb:P62993
gptkbp:bfsParent	gptkb:RAS_signaling_pathway
gptkbp:bfsLayer	6