|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CEK
gptkb:FLG
gptkb:CD331
HBGFR
bFGF-R-1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Kallmann_syndrome
gptkb:Pfeiffer_syndrome
gptkb:osteoglophonic_dysplasia
|
|
gptkbp:biologicalProcess
|
cell proliferation
embryonic development
signal transduction
ATP binding
protein tyrosine kinase activity
skeletal system development
urogenital system development
neuron differentiation
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
integral component of membrane
|
|
gptkbp:encodes
|
gptkb:FGFR1_protein
|
|
gptkbp:Entrez_Gene_ID
|
2260
ENSG00000077782
|
|
gptkbp:fullName
|
fibroblast growth factor receptor 1
|
|
gptkbp:function
|
gptkb:receptor_tyrosine_kinase
cell differentiation
wound healing
angiogenesis
cell growth regulation
|
|
gptkbp:HGNC_ID
|
gptkb:FGFR1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FGFR1 gene
|
|
gptkbp:locatedOnChromosome
|
8
8p11.23
|
|
gptkbp:mutationAssociatedWith
|
developmental disorders
endocrine disorders
|
|
gptkbp:numberOfExons
|
19
|
|
gptkbp:OMIM
|
136350
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Fgfr1
rat Fgfr1
zebrafish fgfr1a
|
|
gptkbp:pathway
|
gptkb:RAS_signaling_pathway
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:FGF_signaling_pathway
|
|
gptkbp:proteinFamily
|
fibroblast growth factor receptor family
|
|
gptkbp:RefSeq
|
NM_023110
|
|
gptkbp:UniProtID
|
P11362
|
|
gptkbp:bfsParent
|
gptkb:FGFR
|
|
gptkbp:bfsLayer
|
6
|