|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:TKF
gptkb:CD334
gptkb:JTK2
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:rhabdomyosarcoma
hepatocellular carcinoma
|
|
gptkbp:biologicalProcess
|
cell differentiation
cell proliferation
signal transduction
protein kinase activity
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:encodes
|
gptkb:FGFR4_protein
|
|
gptkbp:Entrez_Gene_ID
|
2264
ENSG00000160867
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skeletal_muscle
liver
|
|
gptkbp:fullName
|
fibroblast growth factor receptor 4
|
|
gptkbp:function
|
receptor tyrosine kinase activity
fibroblast growth factor binding
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:3686
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FGFR4 gene
|
|
gptkbp:length
|
802 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_5
5q35.2
|
|
gptkbp:mutationAssociatedWith
|
drug resistance
tumor progression
|
|
gptkbp:OMIM
|
134935
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Fgfr4
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:FGF_signaling_pathway
|
|
gptkbp:proteinFamily
|
fibroblast growth factor receptor family
|
|
gptkbp:targetOfDrug
|
FGFR inhibitors
|
|
gptkbp:UniProtID
|
P22455
|
|
gptkbp:bfsParent
|
gptkb:FGFR
|
|
gptkbp:bfsLayer
|
6
|