|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
KS3
HBGF-4
HSTF1
|
|
gptkbp:associatedWith
|
gptkb:cancer
limb development
|
|
gptkbp:biologicalProcess
|
cell differentiation
MAPK cascade
growth factor activity
|
|
gptkbp:cellularComponent
|
extracellular region
|
|
gptkbp:discoveredBy
|
T. Shimizu et al.
|
|
gptkbp:discoveredIn
|
1989
|
|
gptkbp:encodes
|
fibroblast growth factor 4 protein
|
|
gptkbp:Entrez_Gene_ID
|
2249
ENSG00000138685
|
|
gptkbp:expressedIn
|
gptkb:placenta
embryonic stem cells
|
|
gptkbp:fullName
|
fibroblast growth factor 4
|
|
gptkbp:function
|
cell proliferation
embryonic development
angiogenesis
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:3667
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FGF4 gene
|
|
gptkbp:interactsWith
|
gptkb:FGFR3
gptkb:FGFR1
gptkb:FGFR4
gptkb:FGFR2
|
|
gptkbp:length
|
3 exons
|
|
gptkbp:locatedOnChromosome
|
chromosome 11
|
|
gptkbp:mutationAssociatedWith
|
oncogenic transformation
skeletal dysplasia in dogs
|
|
gptkbp:OMIM
|
164980
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Fgf4
|
|
gptkbp:pathway
|
gptkb:PI3K-Akt_signaling_pathway
gptkb:Ras_signaling_pathway
gptkb:FGF_signaling_pathway
|
|
gptkbp:proteinFamily
|
gptkb:fibroblast_growth_factor_family
|
|
gptkbp:RefSeq
|
NM_002007
|
|
gptkbp:regulates
|
cell survival
cell migration
mesoderm formation
|
|
gptkbp:significance
|
implicated in tumorigenesis
associated with canine chondrodysplasia
|
|
gptkbp:species
|
gptkb:human
|
|
gptkbp:UniProtID
|
P08620
|
|
gptkbp:bfsParent
|
gptkb:FGF4
|
|
gptkbp:bfsLayer
|
7
|