Cyclin D

URI: https://gptkb.org/entity/Cyclin_D

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein cell cycle regulator
gptkbp:activatedBy	growth factors
gptkbp:binds	gptkb:CDK4 gptkb:CDK6
gptkbp:degradedBy	gptkb:ubiquitin-proteasome_pathway
gptkbp:encodedBy	gptkb:CCND1_gene
gptkbp:familyMember	cyclins
gptkbp:foundIn	eukaryotic cells
gptkbp:hasIsoform	gptkb:Cyclin_D2 gptkb:Cyclin_D3 gptkb:Cyclin_D1
https://www.w3.org/2000/01/rdf-schema#label	Cyclin D
gptkbp:inhibitedBy	gptkb:CDK_inhibitors_(CKIs)
gptkbp:locale	gptkb:nucleus gptkb:cytoplasm
gptkbp:overexpressedIn	gptkb:cancer
gptkbp:phosphorylates	gptkb:retinoblastoma_protein_(pRb)
gptkbp:promotion	gptkb:G1/S_transition
gptkbp:regulates	cell cycle
gptkbp:bfsParent	gptkb:WAF1_gene
gptkbp:bfsLayer	6