Cyclin D-CDK4 complex

GPTKB entity

Statements (15)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy mitogenic signals
gptkbp:component gptkb:Cyclin_D
gptkb:CDK4
gptkbp:function regulation of cell cycle
phosphorylation of retinoblastoma protein
https://www.w3.org/2000/01/rdf-schema#label Cyclin D-CDK4 complex
gptkbp:inhibitedBy CDK inhibitors
gptkbp:involvedIn G1 phase progression
gptkbp:location gptkb:nucleus
gptkbp:regulates gptkb:G1/S_transition
gptkbp:relatedTo cell proliferation
cancer development
gptkbp:bfsParent gptkb:CDK4
gptkbp:bfsLayer 7