Statements (62)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Cyclin-dependent_kinase
|
| gptkbp:associated_with |
gptkb:Oncology
gptkb:Colorectal_cancer Breast cancer Lung cancer Prostate cancer |
| gptkbp:bioavailability |
Proteasome
|
| gptkbp:function |
Regulatory protein
|
| gptkbp:genetic_studies |
Associated with various cancers
|
| https://www.w3.org/2000/01/rdf-schema#label |
Cyclin D2
|
| gptkbp:influences |
Cellular response to growth factors
|
| gptkbp:initiated_by |
Apoptosis
Cell cycle arrest Cell senescence |
| gptkbp:interacts_with |
gptkb:CDK6
CDK4 E2 F transcription factors RB protein |
| gptkbp:involved_in |
Immune response
Metastasis Hematopoiesis Cellular metabolism DNA damage response Developmental processes Aging process Cellular stress response Cellular communication Neurogenesis Tumorigenesis Cellular response to stress Cellular signaling pathways Cellular organization G1 phase Stem cell maintenance Cellular homeostasis Tissue repair Endocrine signaling Cellular differentiation Tumor growth Cellular aging Cellular dynamics Cellular interactions Cellular architecture Cellular signaling networks Apoptotic signaling pathways Cellular adaptations Cellular responses to stimuli G1/ S transition |
| gptkbp:is_expressed_in |
Various tissues
Regulated by oncogenes Regulated by tumor suppressors Regulated by micro RNAs |
| gptkbp:located_in |
gptkb:Atom
|
| gptkbp:overexpression |
Linked to cancer progression
|
| gptkbp:part_of |
Cell cycle
|
| gptkbp:promoter |
gptkb:CCND2
|
| gptkbp:promotes |
Cell proliferation
Cell cycle progression |
| gptkbp:regulates |
Cell division
Transcription factors |
| gptkbp:bfsParent |
gptkb:CDK6
|
| gptkbp:bfsLayer |
7
|