|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
P450IIC19
S-mephenytoin 4'-hydroxylase
CYP2C19A
|
|
gptkbp:associatedWith
|
gptkb:cyclophosphamide
gptkb:methadone
gptkb:progesterone
gptkb:cardiovascular_disease
gptkb:citalopram
gptkb:escitalopram
gptkb:chloramphenicol
gptkb:phenytoin
gptkb:voriconazole
gptkb:warfarin
gptkb:nifedipine
gptkb:omeprazole
gptkb:sertraline
gptkb:clopidogrel
gptkb:pantoprazole
gptkb:tamoxifen
gptkb:estradiol
gptkb:amitriptyline
gptkb:imipramine
gptkb:lansoprazole
gptkb:rabeprazole
gptkb:diazepam
gptkb:topiramate
gptkb:carisoprodol
gptkb:nelfinavir
gptkb:mephenytoin
gptkb:proguanil
gptkb:clomipramine
gptkb:trimipramine
gptkb:moclobemide
propranolol
peptic ulcer
phenobarbital
adverse drug reaction
nicardipine
testosterone
drug toxicity
poor metabolizer phenotype
ultrarapid metabolizer phenotype
phenprocoumon
|
|
gptkbp:discoveredBy
|
Yasumori et al.
|
|
gptkbp:encodes
|
gptkb:cytochrome_P450_2C19
|
|
gptkbp:Entrez_Gene_ID
|
1557
|
|
gptkbp:expressedIn
|
gptkb:small_intestine
liver
|
|
gptkbp:firstDescribed
|
1994
|
|
gptkbp:hasPolymorphism
|
drug response
antidepressant metabolism
proton pump inhibitor metabolism
clopidogrel metabolism
|
|
gptkbp:HGNC_ID
|
2621
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CYP2C19 gene
|
|
gptkbp:involvedIn
|
drug metabolism
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_10
10q23.33
|
|
gptkbp:memberOf
|
gptkb:cytochrome_P450_superfamily
|
|
gptkbp:OMIM
|
124020
|
|
gptkbp:orthologInMouse
|
gptkb:Cyp2c29
|
|
gptkbp:UniProtID
|
gptkb:P33261
|
|
gptkbp:bfsParent
|
gptkb:ENSG00000101972
gptkb:cytochrome_P450_2C19
gptkb:cytochrome_P450_family_2_subfamily_C_member_19
|
|
gptkbp:bfsLayer
|
7
|