mephenytoin

GPTKB entity

Statements (37)
Predicate Object
gptkbp:instanceOf anticonvulsant
hydantoin derivative
gptkbp:ATCCode N03AB03
gptkbp:CASNumber 50-12-4
gptkbp:chemicalFormula C12H12N2O2
gptkbp:contraindication porphyria
gptkbp:discoveredBy gptkb:H._Houston_Merritt
gptkb:Tracy_Putnam
gptkbp:discoveredIn 1940s
gptkbp:eliminationHalfLife 7-15 hours
gptkbp:hasInChIKey QXDMGPKYFZVEMY-UHFFFAOYSA-N
gptkbp:hasSMILES CC1(C(=O)NC(=O)N1C)C2=CC=CC=C2
https://www.w3.org/2000/01/rdf-schema#label mephenytoin
gptkbp:IUPACName 5-ethyl-3-methyl-5-phenyl-imidazolidine-2,4-dione
gptkbp:legalStatus prescription only
gptkbp:meltingPoint 162-164°C
gptkbp:metabolism gptkb:CYP2C19
gptkbp:molecularWeight 216.24 g/mol
gptkbp:pregnancyCategory D (US)
gptkbp:PubChem_CID 4057
CHEMBL1201
3917
DB00334
gptkbp:relatedTo gptkb:phenytoin
ethotoin
gptkbp:retired risk of severe adverse effects
gptkbp:routeOfAdministration oral
gptkbp:sideEffect rash
drowsiness
ataxia
gptkbp:status withdrawn in many countries
gptkbp:synonym 3-methyl-5-ethyl-5-phenylhydantoin
Mesantoin
gptkbp:UNII 6Q6P4776YS
gptkbp:usedFor treatment of epilepsy
gptkbp:bfsParent gptkb:CYP2C19
gptkbp:bfsLayer 6