|
gptkbp:instanceOf
|
gptkb:chemical_compound
gptkb:antibiotic
|
|
gptkbp:aroma
|
odorless
|
|
gptkbp:ATCCode
|
J01BA01
|
|
gptkbp:CASNumber
|
56-75-7
|
|
gptkbp:chemicalFormula
|
C11H12Cl2N2O5
|
|
gptkbp:color
|
white
|
|
gptkbp:contraindication
|
pregnancy
newborns
hypersensitivity
liver dysfunction
|
|
gptkbp:discoveredBy
|
gptkb:Paul_Ehrlich
|
|
gptkbp:discoveredIn
|
1947
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
gptkbp:has_stereochemistry
|
D-threo
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
chloramphenicol
|
|
gptkbp:KEGGID
|
D00202
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:marketedAs
|
1949
|
|
gptkbp:mechanismOfAction
|
inhibits protein synthesis
|
|
gptkbp:meltingPoint
|
150°C
|
|
gptkbp:MeSH_ID
|
gptkb:D002683
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
323.13 g/mol
|
|
gptkbp:notRecommendedFor
|
food-producing animals
|
|
gptkbp:origin
|
gptkb:Streptomyces_venezuelae
|
|
gptkbp:patentExpired
|
true
|
|
gptkbp:PubChem_CID
|
5959
DB00446
CHEBI:17698
|
|
gptkbp:riskOfResistance
|
high
|
|
gptkbp:routeOfAdministration
|
oral
topical
intravenous
|
|
gptkbp:sideEffect
|
gptkb:gray_baby_syndrome
aplastic anemia
bone marrow suppression
|
|
gptkbp:solubility
|
2.5 g/L
|
|
gptkbp:synonym
|
gptkb:Chloromycetin
D-threo-2,2-dichloro-N-(β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl)acetamide
|
|
gptkbp:target
|
bacterial ribosome
|
|
gptkbp:UNII
|
362O9ITL9D
|
|
gptkbp:usedFor
|
gptkb:rickettsial_infections
meningitis
typhoid fever
bacterial infections
|
|
gptkbp:usedInVeterinaryMedicine
|
true
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:23S_rRNA
gptkb:Chloromycetin
gptkb:Streptomyces_venezuelae
gptkb:Yersinia_pseudotuberculosis
|
|
gptkbp:bfsLayer
|
6
|