trimipramine

GPTKB entity

Statements (40)
Predicate Object
gptkbp:instanceOf antidepressant
gptkbp:approvedBy 1961
gptkbp:ATCCode N06AA06
gptkbp:brand gptkb:Surmontil
gptkbp:CASNumber 739-71-9
gptkbp:category antihistamine
antidepressant
tricyclic compound
gptkbp:chemicalFormula C20H26N2
gptkbp:contraindication gptkb:arrhythmias
recent myocardial infarction
mania
gptkbp:discoveredBy gptkb:Ciba-Geigy
gptkbp:eliminationHalfLife 8–24 hours
gptkbp:excretion urine
https://www.w3.org/2000/01/rdf-schema#label trimipramine
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction antihistamine
norepinephrine reuptake inhibitor
anticholinergic
gptkbp:metabolism liver
gptkbp:molecularWeight 294.44 g/mol
gptkbp:pregnancyCategory C (US)
gptkbp:proteinBinding 95%
gptkbp:PubChem_CID 5556
DB00726
gptkbp:routeOfAdministration oral
gptkbp:sideEffect constipation
dizziness
weight gain
drowsiness
dry mouth
gptkbp:synonym gptkb:Surmontil
trimipramine maleate
gptkbp:UNII 3Z8ZQ1B41X
gptkbp:usedFor gptkb:depression
insomnia
anxiety disorders
gptkbp:bfsParent gptkb:tricyclic_antidepressants
gptkbp:bfsLayer 6