Statements (54)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
proton pump inhibitor |
| gptkbp:approvedBy |
1997
|
| gptkbp:ATCCode |
A02BC04
|
| gptkbp:bioavailability |
52%
|
| gptkbp:brand |
gptkb:Acidil
Acidil Plus Acidil-20 Acidil-DS Acidil-DSR Acidil-DSR Plus Acidil-DSR-20 Acidil-DSR-DS Acidil-DSR-DSR Acidil-DSR-DSR Plus Acidil-DSR-DSR-20 Acidil-DSR-DSR-DS Acidil-DSR-DSR-DSR Acidil-DSR-DSR-IT Acidil-DSR-DSR-ITR Acidil-DSR-DSR-L Acidil-DSR-IT Acidil-DSR-ITR Acidil-DSR-L Acidil-IT Acidil-ITR Acidil-L Acidil-R Pariet |
| gptkbp:CASNumber |
117976-89-3
|
| gptkbp:chemicalFormula |
C18H21N3O3S
|
| gptkbp:discoveredBy |
gptkb:Eisai
|
| gptkbp:eliminationHalfLife |
1-2 hours
|
| gptkbp:excretion |
urine
feces |
| https://www.w3.org/2000/01/rdf-schema#label |
rabeprazole
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits H+/K+ ATPase in gastric parietal cells
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
359.44 g/mol
|
| gptkbp:pregnancyCategory |
C (US)
B3 (Australia) |
| gptkbp:proteinBinding |
96.3%
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
nausea
diarrhea abdominal pain headache rash |
| gptkbp:usedFor |
gptkb:Zollinger-Ellison_syndrome
gptkb:gastroesophageal_reflux_disease gptkb:peptic_ulcer_disease |
| gptkbp:bfsParent |
gptkb:CYP3A4
|
| gptkbp:bfsLayer |
5
|