Statements (57)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
hormone
estrogen |
| gptkbp:affects |
cardiovascular system
cognitive function skin health mood bone density cholesterol levels |
| gptkbp:brand |
gptkb:Climara
gptkb:Estrace gptkb:Estraderm gptkb:Estrofem gptkb:Vivelle-Dot |
| gptkbp:CASNumber |
50-28-2
|
| gptkbp:chemicalFormula |
C18H24O2
|
| gptkbp:discoveredBy |
gptkb:Adolf_Butenandt
|
| gptkbp:discoveredIn |
1935
|
| gptkbp:excretion |
urine
|
| gptkbp:foundIn |
humans
other mammals |
| https://www.w3.org/2000/01/rdf-schema#label |
estradiol
|
| gptkbp:IUPACName |
estra-1,3,5(10)-triene-3,17β-diol
|
| gptkbp:meltingPoint |
173.5 °C
|
| gptkbp:MeSH_ID |
D004967
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
272.38 g/mol
|
| gptkbp:predecessor |
gptkb:androstenedione
testosterone |
| gptkbp:producedBy |
gptkb:placenta
adrenal glands ovaries testes |
| gptkbp:PubChem_CID |
gptkb:CHEMBL691
gptkb:DB00783 5757 CHEBI:16469 |
| gptkbp:recipient |
estrogen receptor alpha
estrogen receptor beta |
| gptkbp:regulates |
reproductive system
menstrual cycle |
| gptkbp:routeOfAdministration |
oral
intramuscular transdermal vaginal |
| gptkbp:sideEffect |
nausea
headache breast tenderness increased risk of blood clots increased risk of breast cancer increased risk of stroke |
| gptkbp:UNII |
4TI98Z838E
|
| gptkbp:usedFor |
contraception
hormone replacement therapy treatment of menopausal symptoms treatment of osteoporosis |
| gptkbp:bfsParent |
gptkb:E2
|
| gptkbp:bfsLayer |
5
|