Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:discoveredIn |
1940
|
| gptkbp:EC_number |
3.5.2.6
|
| gptkbp:encodedBy |
gptkb:bla_gene
|
| gptkbp:foundIn |
gptkb:Bacteria
|
| gptkbp:function |
hydrolyzes beta-lactam antibiotics
|
| gptkbp:hasType |
gptkb:TEM_beta-lactamase
gptkb:AmpC_beta-lactamase gptkb:CTX-M_beta-lactamase gptkb:KPC_beta-lactamase gptkb:NDM_beta-lactamase gptkb:OXA_beta-lactamase gptkb:SHV_beta-lactamase |
| gptkbp:inhibitedBy |
gptkb:clavulanic_acid
gptkb:sulbactam tazobactam |
| gptkbp:mechanismOfAction |
breaks beta-lactam ring
|
| gptkbp:producedBy |
Gram-negative bacteria
Gram-positive bacteria |
| gptkbp:resistantTo |
gptkb:cephalosporins
gptkb:monobactams penicillins carbapenems |
| gptkbp:significance |
antibiotic resistance
|
| gptkbp:subclassOf |
gptkb:hydrolase
antibiotic resistance protein |
| gptkbp:bfsParent |
gptkb:Enzymes
|
| gptkbp:bfsLayer |
6
|
| https://www.w3.org/2000/01/rdf-schema#label |
Beta-lactamase
|