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gptkbp:instanceOf
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gptkb:enzyme
beta-lactamase
|
|
gptkbp:abbreviation
|
gptkb:NDM
|
|
gptkbp:associatedWith
|
community-acquired infections
hospital-acquired infections
|
|
gptkbp:class
|
Ambler class B beta-lactamase
|
|
gptkbp:cofactor
|
zinc
|
|
gptkbp:detects
|
PCR
phenotypic tests
|
|
gptkbp:discoveredBy
|
Yong et al.
|
|
gptkbp:discoveredIn
|
2008
|
|
gptkbp:encodedBy
|
blaNDM gene
|
|
gptkbp:firstReported
|
gptkb:India
gptkb:Sweden
|
|
gptkbp:foundIn
|
gptkb:Enterobacteriaceae
gptkb:Bacteria
gptkb:Acinetobacter_baumannii
gptkb:Klebsiella_pneumoniae
|
|
gptkbp:fullName
|
gptkb:New_Delhi_metallo-beta-lactamase
|
|
gptkbp:hasVariant
|
gptkb:NDM-1
gptkb:NDM-2
gptkb:NDM-5
gptkb:NDM-7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NDM beta-lactamase
|
|
gptkbp:inhibitedBy
|
gptkb:clavulanic_acid
gptkb:sulbactam
gptkb:EDTA
tazobactam
|
|
gptkbp:mechanismOfAction
|
hydrolyzes beta-lactam ring
|
|
gptkbp:namedAfter
|
gptkb:New_Delhi
|
|
gptkbp:publicHealthConcern
|
antibiotic resistance
|
|
gptkbp:publicHealthResponse
|
antibiotic stewardship
infection control measures
|
|
gptkbp:resistantTo
|
gptkb:beta-lactam_antibiotics
carbapenem antibiotics
|
|
gptkbp:spreadTo
|
plasmids
|
|
gptkbp:variant
|
metallo-beta-lactamase
|
|
gptkbp:bfsParent
|
gptkb:Beta-lactamase
|
|
gptkbp:bfsLayer
|
7
|