Statements (26)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:antibiotic
|
gptkbp:administeredBy |
intramuscular injection
intravenous injection |
gptkbp:approvedBy |
gptkb:FDA
|
gptkbp:category |
antibacterial drug
|
gptkbp:discoveredIn |
1970s
|
gptkbp:example |
gptkb:aztreonam
carumonam tigemonam |
gptkbp:features |
patients with penicillin allergy
|
gptkbp:hasCoreCity |
monocyclic beta-lactam ring
|
https://www.w3.org/2000/01/rdf-schema#label |
monobactams
|
gptkbp:mechanismOfAction |
inhibit bacterial cell wall synthesis
|
gptkbp:notEffectiveAgainst |
Gram-positive bacteria
anaerobic bacteria anaerobes Gram-positive cocci |
gptkbp:resistantTo |
some beta-lactamases
|
gptkbp:sideEffect |
nausea
vomiting rash liver enzyme elevation |
gptkbp:spectrumOfActivity |
narrow
|
gptkbp:usedFor |
treatment of Gram-negative bacterial infections
|
gptkbp:bfsParent |
gptkb:Beta-lactams
|
gptkbp:bfsLayer |
5
|