monobactams

GPTKB entity

Statements (26)
Predicate Object
gptkbp:instanceOf gptkb:antibiotic
gptkbp:administeredBy intramuscular injection
intravenous injection
gptkbp:approvedBy gptkb:FDA
gptkbp:category antibacterial drug
gptkbp:discoveredIn 1970s
gptkbp:example gptkb:aztreonam
carumonam
tigemonam
gptkbp:features patients with penicillin allergy
gptkbp:hasCoreCity monocyclic beta-lactam ring
https://www.w3.org/2000/01/rdf-schema#label monobactams
gptkbp:mechanismOfAction inhibit bacterial cell wall synthesis
gptkbp:notEffectiveAgainst Gram-positive bacteria
anaerobic bacteria
anaerobes
Gram-positive cocci
gptkbp:resistantTo some beta-lactamases
gptkbp:sideEffect nausea
vomiting
rash
liver enzyme elevation
gptkbp:spectrumOfActivity narrow
gptkbp:usedFor treatment of Gram-negative bacterial infections
gptkbp:bfsParent gptkb:Beta-lactams
gptkbp:bfsLayer 5