Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:antibiotic
|
| gptkbp:administeredBy |
intramuscular injection
intravenous injection |
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:category |
gptkb:antibacterial_drug
|
| gptkbp:discoveredIn |
1970s
|
| gptkbp:example |
gptkb:aztreonam
carumonam tigemonam |
| gptkbp:features |
patients with penicillin allergy
|
| gptkbp:hasCoreCity |
monocyclic beta-lactam ring
|
| gptkbp:mechanismOfAction |
inhibit bacterial cell wall synthesis
|
| gptkbp:notEffectiveAgainst |
Gram-positive bacteria
anaerobic bacteria anaerobes Gram-positive cocci |
| gptkbp:resistantTo |
some beta-lactamases
|
| gptkbp:sideEffect |
nausea
vomiting rash liver enzyme elevation |
| gptkbp:spectrumOfActivity |
narrow
|
| gptkbp:usedFor |
treatment of Gram-negative bacterial infections
|
| gptkbp:bfsParent |
gptkb:IMP-I
gptkb:beta-lactam_antibiotics gptkb:Beta-lactamase |
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
monobactams
|