|
gptkbp:instanceOf
|
gptkb:antibiotic
beta-lactamase inhibitor
|
|
gptkbp:ATCCode
|
gptkb:J01CG01
|
|
gptkbp:CASNumber
|
61177-45-5
|
|
gptkbp:category
|
gptkb:drug
antibiotic adjuvant
beta-lactam compound
|
|
gptkbp:chemicalFormula
|
C8H9NO5
|
|
gptkbp:discoveredBy
|
British scientists
|
|
gptkbp:discoveredIn
|
1976
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
clavulanic acid
|
|
gptkbp:IUPACName
|
(2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
|
|
gptkbp:KEGGID
|
D00255
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits beta-lactamase enzymes
|
|
gptkbp:meltingPoint
|
64–66 °C
|
|
gptkbp:molecularWeight
|
199.17 g/mol
|
|
gptkbp:notEffectiveAgainst
|
bacteria lacking beta-lactamase
|
|
gptkbp:producedBy
|
gptkb:Streptomyces_clavuligerus
|
|
gptkbp:PubChem_CID
|
5280980
CHEMBL1276
DB00766
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
|
|
gptkbp:sideEffect
|
nausea
diarrhea
allergic reactions
|
|
gptkbp:UNII
|
2355430N2D
|
|
gptkbp:used_in
|
gptkb:amoxicillin
gptkb:ticarcillin
|
|
gptkbp:usedFor
|
bacterial infections
|
|
gptkbp:bfsParent
|
gptkb:Amoxicillin
|
|
gptkbp:bfsLayer
|
5
|