Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:enzymeClassification |
beta-lactamase
|
| gptkbp:firstDescribed |
1989
|
| gptkbp:foundIn |
gptkb:Enterobacteriaceae
gptkb:Bacteria gptkb:Klebsiella_pneumoniae |
| gptkbp:function |
hydrolyzes beta-lactam antibiotics
|
| https://www.w3.org/2000/01/rdf-schema#label |
CTX-M beta-lactamase
|
| gptkbp:inhibitedBy |
gptkb:clavulanic_acid
tazobactam avibactam |
| gptkbp:molecularWeight |
~29 kDa
|
| gptkbp:namedAfter |
Cefotaximase
|
| gptkbp:notableGroup |
gptkb:CTX-M-15
CTX-M-14 |
| gptkbp:proteinFamily |
blaCTX-M
|
| gptkbp:resistantTo |
gptkb:cephalosporins
penicillins |
| gptkbp:significance |
antibiotic resistance
|
| gptkbp:spreadTo |
plasmids
|
| gptkbp:substrate |
expanded-spectrum cephalosporins
|
| gptkbp:bfsParent |
gptkb:Beta-lactamase
|
| gptkbp:bfsLayer |
7
|