Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:beta-lactamase_inhibitor
gptkb:drug |
| gptkbp:ATCCode |
gptkb:J01CG01
|
| gptkbp:CASNumber |
gptkb:68373-14-8
|
| gptkbp:category |
antibiotic adjuvant
|
| gptkbp:chemicalFormula |
gptkb:C8H11NO5S
|
| gptkbp:contraindication |
hypersensitivity to beta-lactams
|
| gptkbp:discoveredBy |
1980s
|
| gptkbp:eliminationHalfLife |
1 hour
|
| gptkbp:excretion |
renal
|
| gptkbp:indication |
bacterial infections
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits beta-lactamase enzymes
|
| gptkbp:metabolism |
not significantly metabolized
|
| gptkbp:molecularWeight |
233.25 g/mol
|
| gptkbp:PubChem_CID |
CHEMBL1201192
130313 DB00710 |
| gptkbp:routeOfAdministration |
intramuscular
intravenous |
| gptkbp:sideEffect |
diarrhea
allergic reaction rash pain at injection site |
| gptkbp:UNII |
98DX6S6A0N
|
| gptkbp:used_in |
gptkb:cefoperazone
gptkb:ampicillin |
| gptkbp:bfsParent |
gptkb:IMP-I
gptkb:ampicillin-sulbactam gptkb:Beta-lactamase gptkb:ampicillin |
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
sulbactam
|