|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:ATCCode
|
J01DB
|
|
gptkbp:class
|
cephalosporin
fifth-generation cephalosporin
first-generation cephalosporin
fourth-generation cephalosporin
second-generation cephalosporin
|
|
gptkbp:contraindication
|
penicillin allergy
|
|
gptkbp:derivedFrom
|
gptkb:Cephalosporium_acremonium
|
|
gptkbp:discoveredBy
|
gptkb:Giuseppe_Brotzu
|
|
gptkbp:discoveredIn
|
1945
|
|
gptkbp:eliminatedIn
|
renal
|
|
gptkbp:example
|
gptkb:cefepime
gptkb:ceftaroline
gptkb:ceftriaxone
gptkb:cephalexin
cefuroxime
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
cephalosporins
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibit cell wall synthesis
|
|
gptkbp:metabolism
|
hepatic
|
|
gptkbp:pregnancyCategory
|
B (varies by drug)
|
|
gptkbp:resistantTo
|
beta-lactamase production
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular
intravenous
|
|
gptkbp:sideEffect
|
allergic reaction
rash
gastrointestinal upset
|
|
gptkbp:spectrumOfActivity
|
broad-spectrum
|
|
gptkbp:subclassOf
|
gptkb:antibiotic
|
|
gptkbp:usedFor
|
bacterial infections
|
|
gptkbp:bfsParent
|
gptkb:Beta-lactams
|
|
gptkbp:bfsLayer
|
5
|