Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
beta-lactamase |
| gptkbp:alternativeName |
gptkb:Klebsiella_pneumoniae_carbapenemase
KPC enzyme |
| gptkbp:associatedWith |
multidrug resistance
hospital-acquired infections |
| gptkbp:discoveredIn |
gptkb:Klebsiella_pneumoniae
|
| gptkbp:encodedBy |
blaKPC gene
|
| gptkbp:firstDescribed |
1996
|
| gptkbp:foundIn |
gptkb:Enterobacteriaceae
gptkb:Pseudomonas_aeruginosa |
| https://www.w3.org/2000/01/rdf-schema#label |
KPC beta-lactamase
|
| gptkbp:inhibitedBy |
gptkb:vaborbactam
gptkb:clavulanic_acid gptkb:sulbactam tazobactam avibactam |
| gptkbp:mechanismOfAction |
hydrolyzes beta-lactam ring
|
| gptkbp:publicHealthConcern |
antibiotic resistance
|
| gptkbp:resistantTo |
gptkb:cephalosporins
penicillins carbapenem antibiotics |
| gptkbp:spreadTo |
plasmids
|
| gptkbp:subclassOf |
class A beta-lactamase
|
| gptkbp:bfsParent |
gptkb:Beta-lactamase
|
| gptkbp:bfsLayer |
7
|