|
gptkbp:instanceOf
|
gptkb:protein
gptkb:G_protein-coupled_receptor
|
|
gptkbp:agonizedBy
|
gptkb:methadone
gptkb:morphine
gptkb:buprenorphine
amphetamine
fentanyl
|
|
gptkbp:alternativeName
|
gptkb:OPRM1
MOR
|
|
gptkbp:binds
|
gptkb:methadone
gptkb:morphine
gptkb:enkephalins
gptkb:naloxone
gptkb:buprenorphine
gptkb:naltrexone
gptkb:beta-endorphin
amphetamine
fentanyl
endorphins
|
|
gptkbp:discoveredBy
|
gptkb:Candace_Pert
|
|
gptkbp:discoveredIn
|
1973
|
|
gptkbp:encodedBy
|
gptkb:OPRM1_gene
|
|
gptkbp:enemyOf
|
gptkb:naloxone
gptkb:naltrexone
|
|
gptkbp:Entrez_Gene_ID
|
4988
|
|
gptkbp:expressedIn
|
gptkb:spinal_cord
brain
gastrointestinal tract
|
|
gptkbp:foundIn
|
gptkb:human
gptkb:mouse
right
|
|
gptkbp:function
|
mediates analgesia
mediates euphoria
mediates miosis
mediates physical dependence
mediates reduced gastrointestinal motility
mediates respiratory depression
mediates sedation
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
mu-opioid receptor
|
|
gptkbp:locatedIn
|
central nervous system
peripheral nervous system
|
|
gptkbp:locatedOnChromosome
|
gptkb:6q25.2
|
|
gptkbp:memberOf
|
gptkb:opioid_receptor_family
|
|
gptkbp:PDB
|
gptkb:4DKL
5C1M
|
|
gptkbp:relatedTo
|
gptkb:nociceptin_receptor
gptkb:delta-opioid_receptor
gptkb:kappa-opioid_receptor
|
|
gptkbp:UniProtID
|
gptkb:P35372
|
|
gptkbp:bfsParent
|
gptkb:Naloxone
gptkb:opioid
|
|
gptkbp:bfsLayer
|
6
|