|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
MOR
MOR-1
mu opioid receptor
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
addiction
analgesia
alcohol dependence
pain perception
opioid dependence
opioid addiction
heroin dependence
pain sensitivity
|
|
gptkbp:chromosomeArm
|
6q24-q25
|
|
gptkbp:clinicalTrialPhase
|
pharmacogenomics of opioid response
|
|
gptkbp:discoveredBy
|
Yasmin Hurd
|
|
gptkbp:discoveredIn
|
1992
|
|
gptkbp:encodes
|
gptkb:mu-opioid_receptor
|
|
gptkbp:Entrez_Gene_ID
|
4988
ENSG00000112038
|
|
gptkbp:expressedIn
|
gptkb:spinal_cord
brain
peripheral nervous system
|
|
gptkbp:fullName
|
opioid receptor mu 1
|
|
gptkbp:function
|
signal transduction
G-protein coupled receptor activity
opioid receptor activity
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasPolymorphism
|
A118G
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:8156
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
OPRM1 gene
|
|
gptkbp:length
|
7 exons
|
|
gptkbp:locatedOnChromosome
|
6
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Oprm1
|
|
gptkbp:product
|
gptkb:mu-opioid_receptor
|
|
gptkbp:proteinFamily
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:target
|
gptkb:methadone
gptkb:morphine
gptkb:naloxone
gptkb:buprenorphine
gptkb:naltrexone
amphetamine
fentanyl
endogenous opioids
|
|
gptkbp:UniProtID
|
gptkb:P35372
|
|
gptkbp:bfsParent
|
gptkb:opioid
|
|
gptkbp:bfsLayer
|
6
|