Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:composedOf |
gptkb:nociceptin_receptor
gptkb:delta-opioid_receptor gptkb:kappa-opioid_receptor gptkb:mu-opioid_receptor |
| gptkbp:discoveredIn |
1970s
|
| gptkbp:foundIn |
vertebrates
|
| gptkbp:function |
binds endogenous opioids
binds exogenous opioids |
| https://www.w3.org/2000/01/rdf-schema#label |
opioid receptor family
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:memberOf |
gptkb:G_protein-coupled_receptor_superfamily
|
| gptkbp:proteinFamily |
gptkb:OPRD1
gptkb:OPRK1 gptkb:OPRM1 OPRL1 |
| gptkbp:role |
regulation of mood
modulation of pain regulation of stress response regulation of reward |
| gptkbp:structure |
seven transmembrane domains
|
| gptkbp:target |
antagonists
analgesics opioid drugs partial agonists |
| gptkbp:type |
inhibits adenylyl cyclase
activates potassium channels inhibits calcium channels |
| gptkbp:bfsParent |
gptkb:OPRD1_gene
gptkb:OPRL1_gene gptkb:nociceptin_receptor gptkb:delta-opioid_receptor gptkb:mu-opioid_receptor |
| gptkbp:bfsLayer |
7
|