|
gptkbp:instanceOf
|
gptkb:G_protein-coupled_receptor
opioid
|
|
gptkbp:alternativeName
|
gptkb:DOR
gptkb:OPRD1
gptkb:delta-type_opioid_receptor
|
|
gptkbp:encodedBy
|
gptkb:OPRD1_gene
|
|
gptkbp:enemyOf
|
gptkb:naloxone
gptkb:DPDPE
gptkb:SNC80
gptkb:deltorphin_II
gptkb:enkephalin
gptkb:naltrindole
|
|
gptkbp:Entrez_Gene_ID
|
4985
|
|
gptkbp:expressedIn
|
gptkb:striatum
gptkb:spinal_cord
gptkb:cortex
gptkb:dorsal_root_ganglia
brain
central nervous system
hippocampus
peripheral nervous system
amygdala
limbic system
thalamus
|
|
gptkbp:foundIn
|
gptkb:human
gptkb:mouse
right
|
|
gptkbp:function
|
analgesia
regulation of mood
neuroprotection
modulation of pain
|
|
gptkbp:HGNC_ID
|
8123
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
delta-opioid receptor
|
|
gptkbp:ligand
|
gptkb:enkephalins
gptkb:deltorphins
synthetic opioids
|
|
gptkbp:locatedOnChromosome
|
chromosome 1 (human)
|
|
gptkbp:memberOf
|
gptkb:opioid_receptor_family
|
|
gptkbp:OMIM
|
165195
|
|
gptkbp:PDB
|
gptkb:4N6H
gptkb:6PT2
|
|
gptkbp:relatedTo
|
gptkb:kappa-opioid_receptor
gptkb:mu-opioid_receptor
|
|
gptkbp:targetOfDrug
|
pain management
depression treatment
anxiety treatment
|
|
gptkbp:type
|
inhibits adenylyl cyclase
activates potassium channels
inhibits calcium channels
|
|
gptkbp:UniProtID
|
gptkb:P41143
|
|
gptkbp:bfsParent
|
gptkb:Naloxone
gptkb:opioid
|
|
gptkbp:bfsLayer
|
6
|