|
gptkbp:instanceOf
|
gptkb:protein
gptkb:G_protein-coupled_receptor
|
|
gptkbp:binds
|
gptkb:salvinorin_A
gptkb:U-50488
gptkb:dynorphin
gptkb:nalfurafine
|
|
gptkbp:category
|
gptkb:cell_membrane
opioid
neurotransmitter receptor
|
|
gptkbp:discoveredBy
|
gptkb:Avram_Goldstein
|
|
gptkbp:discoveredIn
|
1976
|
|
gptkbp:encodedBy
|
gptkb:OPRK1_gene
|
|
gptkbp:enemyOf
|
gptkb:buprenorphine
gptkb:5'-GNTI
gptkb:JDTic
gptkb:nor-BNI
|
|
gptkbp:Entrez_Gene_ID
|
4986
|
|
gptkbp:foundIn
|
gptkb:human
mammals
|
|
gptkbp:function
|
regulation of mood
modulation of pain
regulation of stress response
regulation of consciousness
|
|
gptkbp:GOID
|
gptkb:GO:0004980
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
kappa-opioid receptor
|
|
gptkbp:locatedIn
|
central nervous system
peripheral nervous system
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_8q11.23
|
|
gptkbp:medicalUse
|
analgesia
antipruritic
potential antidepressant
|
|
gptkbp:PDB
|
gptkb:4DJH
|
|
gptkbp:relatedTo
|
gptkb:nociceptin_receptor
gptkb:delta-opioid_receptor
gptkb:mu-opioid_receptor
|
|
gptkbp:sideEffect
|
hallucinations
dysphoria
diuresis
|
|
gptkbp:symbol
|
gptkb:OPRK1
|
|
gptkbp:UniProtID
|
gptkb:P41145
|
|
gptkbp:bfsParent
|
gptkb:Naloxone
gptkb:opioid
|
|
gptkbp:bfsLayer
|
6
|