Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:endogenous_opioid_peptide
peptide |
| gptkbp:aminoAcidSequence |
Tyr-Gly-Gly-Phe-Leu (leu-enkephalin)
Tyr-Gly-Gly-Phe-Met (met-enkephalin) |
| gptkbp:binds |
gptkb:opioid_receptors
gptkb:delta-opioid_receptor gptkb:mu-opioid_receptor |
| gptkbp:biosynthesized_from |
proenkephalin
|
| gptkbp:category |
neurotransmitter
neuromodulator |
| gptkbp:degradedBy |
enkephalinase
|
| gptkbp:discoveredBy |
gptkb:John_Hughes
gptkb:Hans_Kosterlitz |
| gptkbp:discoveredIn |
1975
|
| gptkbp:effect |
euphoria
analgesia inhibition of neurotransmitter release reduced pain perception |
| gptkbp:example |
leu-enkephalin
met-enkephalin |
| gptkbp:foundIn |
gptkb:spinal_cord
brain |
| gptkbp:function |
pain modulation
regulation of nociception |
| https://www.w3.org/2000/01/rdf-schema#label |
enkephalins
|
| gptkbp:location |
central nervous system
peripheral nervous system |
| gptkbp:precursorProtein |
proenkephalin
|
| gptkbp:relatedTo |
dynorphins
endorphins |
| gptkbp:type |
pentapeptide
|
| gptkbp:bfsParent |
gptkb:Hans_Kosterlitz
gptkb:opioid |
| gptkbp:bfsLayer |
6
|