Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
integrin
|
| gptkbp:alternativeName |
fibronectin receptor
|
| gptkbp:binds |
gptkb:fibronectin
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
gptkb:ITGB1
ITGA5 |
| gptkbp:expressedIn |
many cell types
|
| gptkbp:formsComplexWith |
gptkb:talin
kindlin |
| gptkbp:function |
signal transduction
cell migration cell adhesion |
| gptkbp:hasRole |
embryonic development
immune response extracellular matrix organization |
| https://www.w3.org/2000/01/rdf-schema#label |
α5β1 integrin
|
| gptkbp:involvedIn |
wound healing
angiogenesis tumor metastasis |
| gptkbp:ligand |
fibronectin RGD motif
|
| gptkbp:locale |
gptkb:cell_membrane
|
| gptkbp:modulatedBy |
divalent cations
manganese ions |
| gptkbp:subunit |
gptkb:integrin_beta-1
integrin alpha-5 |
| gptkbp:target |
therapeutic antibodies
|
| gptkbp:bfsParent |
gptkb:integrins
|
| gptkbp:bfsLayer |
7
|