|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:Bone_Sialoprotein_1
gptkb:Eta-1
gptkb:Osteopontin
gptkb:Secreted_Phosphoprotein_1
|
|
gptkbp:associatedWith
|
gptkb:cancer
inflammatory diseases
|
|
gptkbp:biologicalProcess
|
wound healing
cytokine activity
extracellular matrix organization
integrin binding
regulation of biomineral tissue development
|
|
gptkbp:discoveredBy
|
Oldberg et al.
|
|
gptkbp:discoveredIn
|
1986
|
|
gptkbp:encodes
|
gptkb:osteopontin
|
|
gptkbp:Entrez_Gene_ID
|
6696
ENSG00000118785
|
|
gptkbp:expressedIn
|
gptkb:bone
gptkb:kidney
immune cells
|
|
gptkbp:function
|
immune response
cell adhesion
bone remodeling
|
|
gptkbp:GOID
|
GO:0001525
GO:0008284
|
|
gptkbp:hasTranscriptVariant
|
SPP1-201
SPP1-202
|
|
gptkbp:HGNC_ID
|
11255
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SPP1
|
|
gptkbp:interactsWith
|
gptkb:integrins
gptkb:CD44
|
|
gptkbp:length
|
314 amino acids
|
|
gptkbp:locatedOnChromosome
|
4q22.1
|
|
gptkbp:OMIM
|
166490
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Spp1
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:product
|
gptkb:osteopontin
secreted glycoprotein
|
|
gptkbp:regulates
|
upregulated in cancer
upregulated in inflammation
|
|
gptkbp:subcellularLocation
|
gptkb:plasma_membrane
extracellular space
|
|
gptkbp:UniProtID
|
P10451
|
|
gptkbp:bfsParent
|
gptkb:EGR1
|
|
gptkbp:bfsLayer
|
6
|