Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
|
| gptkbp:activatedBy |
guanine nucleotide exchange factors (GEFs)
Rho-associated protein kinase (ROCK) mDia proteins |
| gptkbp:associatedWith |
focal adhesion formation
myosin light chain phosphorylation stress fiber formation cellular contractility |
| https://www.w3.org/2000/01/rdf-schema#label |
RhoA signaling pathway
|
| gptkbp:involves |
gptkb:RhoA_protein
wound healing cancer progression neuronal development cell polarity smooth muscle contraction cellular morphogenesis |
| gptkbp:is_inactivated_by |
GTPase-activating proteins (GAPs)
|
| gptkbp:modulatedBy |
gptkb:integrins
gptkb:G_protein-coupled_receptors_(GPCRs) growth factors extracellular signals |
| gptkbp:partOf |
Rho GTPase signaling pathways
|
| gptkbp:regulates |
gptkb:guanine_nucleotide_dissociation_inhibitors_(GDIs)
cell cycle progression cell migration cell adhesion actin cytoskeleton organization |
| gptkbp:bfsParent |
gptkb:RND3
|
| gptkbp:bfsLayer |
6
|