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gptkbp:instanceOf
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gptkb:protein
|
|
gptkbp:alternativeName
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gptkb:IL6ST
gptkb:interleukin-6_signal_transducer
|
|
gptkbp:component
|
gptkb:cardiotrophin-1_receptor_complex
gptkb:ciliary_neurotrophic_factor_receptor_complex
gptkb:interleukin-11_receptor_complex
gptkb:interleukin-6_receptor_complex
gptkb:leukemia_inhibitory_factor_receptor_complex
gptkb:oncostatin_M_receptor_complex
|
|
gptkbp:discoveredBy
|
early 1990s
|
|
gptkbp:encodedBy
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gptkb:IL6ST_gene
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:form
|
heterodimers
homodimers
|
|
gptkbp:foundIn
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gptkb:Homo_sapiens
|
|
gptkbp:function
|
signal transduction
cytokine receptor activity
|
|
gptkbp:gene
|
gptkb:IL6ST
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
gp130
|
|
gptkbp:interactsWith
|
gptkb:SHC1
gptkb:STAT1
gptkb:SOCS3
gptkb:JAK1
gptkb:STAT3
|
|
gptkbp:locatedOnChromosome
|
gptkb:5q11
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
inflammatory diseases
immunodeficiency
|
|
gptkbp:OMIM
|
600694
|
|
gptkbp:requires
|
gptkb:IL-6_family_cytokine_signaling
|
|
gptkbp:UniProtID
|
P40189
|
|
gptkbp:bfsParent
|
gptkb:interleukin-6
gptkb:human_interleukin-6
|
|
gptkbp:bfsLayer
|
6
|