Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
CD130
Interleukin 6 signal transducer |
| gptkbp:associatedWith |
cytokine receptor activity
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:encodes |
gp130 protein
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000134352
3572 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:function |
signal transduction for interleukin-6 family cytokines
|
| https://www.w3.org/2000/01/rdf-schema#label |
IL6ST gene
|
| gptkbp:interactsWith |
gptkb:IL6
gptkb:CLC gptkb:CT-1 gptkb:OSM gptkb:LIF gptkb:CNTF IL11 |
| gptkbp:involvedIn |
gptkb:JAK/STAT_signaling_pathway
immune response |
| gptkbp:length |
918 amino acids
|
| gptkbp:locatedOnChromosome |
gptkb:5q11.2
|
| gptkbp:memberOf |
type I cytokine receptor family
|
| gptkbp:mutationAssociatedWith |
immunodeficiency
autoimmune disease |
| gptkbp:OMIM |
600694
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Il6st
|
| gptkbp:product |
gptkb:gp130
|
| gptkbp:UniProtID |
P40189
|
| gptkbp:bfsParent |
gptkb:gp130_receptor
|
| gptkbp:bfsLayer |
6
|