|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:gp130
CD130
Interleukin-6 signal transducer
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:domain
|
immunoglobulin-like domain
fibronectin type-III domain
cytokine receptor domain
|
|
gptkbp:encodes
|
gptkb:gp130
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000134352
3572
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:function
|
signal transduction for interleukin-6 family cytokines
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
6010
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IL6ST
|
|
gptkbp:interactsWith
|
gptkb:LIFR
gptkb:IL6R
gptkb:OSMR
CNTFR
CTF1R
|
|
gptkbp:involvedIn
|
gptkb:JAK/STAT_signaling_pathway
immune response
hematopoiesis
|
|
gptkbp:locatedOnChromosome
|
gptkb:5q11
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:molecularWeight
|
130 kDa
|
|
gptkbp:mutationAssociatedWith
|
inflammatory diseases
immunodeficiency
|
|
gptkbp:OMIM
|
600694
|
|
gptkbp:orthologInMouse
|
Il6st
|
|
gptkbp:regulates
|
cell differentiation
cell growth
inflammation
acute phase response
|
|
gptkbp:requires
|
embryonic development
immune system development
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:transmembraneDomains
|
1
|
|
gptkbp:UniProtID
|
P40189
|
|
gptkbp:bfsParent
|
gptkb:gp130_receptor
|
|
gptkbp:bfsLayer
|
6
|