eosinophils

GPTKB entity

Statements (53)
Predicate Object
gptkbp:instanceOf white blood cell
gptkbp:activatedBy gptkb:GM-CSF
gptkb:interleukin-3
gptkb:interleukin-5
gptkbp:associatedWith gptkb:Churg-Strauss_syndrome
gptkb:atopic_dermatitis
eosinophilic esophagitis
chronic rhinosinusitis
helminth infections
gptkbp:contains granules
gptkbp:decreasedIn gptkb:Cushing's_syndrome
gptkbp:discoveredBy gptkb:Paul_Ehrlich
gptkbp:firstDescribed 1879
gptkbp:foundIn blood
tissues
gptkbp:function combat multicellular parasites
modulate allergic inflammatory responses
gptkbp:granuleColor reddish-orange
gptkbp:granuleContent gptkb:eosinophil-derived_neurotoxin
gptkb:eosinophil_cationic_protein
gptkb:eosinophil_peroxidase
gptkb:major_basic_protein
https://www.w3.org/2000/01/rdf-schema#label eosinophils
gptkbp:improves allergic reactions
parasitic infections
gptkbp:lifespan 8-12 days
gptkbp:marking gptkb:CD125
gptkb:Siglec-8
gptkbp:migrateTo sites of inflammation
gptkbp:nucleusShape bilobed
gptkbp:percentageOfLeukocytes 1-4%
gptkbp:producedBy bone marrow
gptkbp:relatedTo asthma
eosinophilia
hypereosinophilic syndrome
eosinopenia
gptkbp:releaseYear cytotoxic proteins
inflammatory mediators
gptkbp:role immune response
antigen presentation
tissue remodeling
gptkbp:stainedBy gptkb:eosin_dye
gptkbp:surfaceProtein gptkb:CCR3
gptkb:CD62L
gptkb:CD44
gptkb:IL-5_receptor
gptkb:CD11b
gptkbp:type granulocyte
gptkbp:bfsParent gptkb:IL5
gptkb:ECA_(Eosinophilic_cytoplasmic_aggregate_in_equine_medicine)
gptkb:ECA_(Eosinophilic_cytoplasmic_aggregate_in_nematode_medicine)
gptkb:ECA_(Eosinophilic_cytoplasmic_aggregate_in_viral_medicine)
gptkbp:bfsLayer 6