Statements (25)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:associatedWith |
gptkb:eosinophilic_granulomatosis_with_polyangiitis
asthma hypereosinophilic syndrome |
gptkbp:binds |
gptkb:interleukin-5
|
gptkbp:encodedBy |
gptkb:CSF2RB_gene
gptkb:IL5RA_gene |
gptkbp:expressedIn |
gptkb:basophils
gptkb:eosinophils |
gptkbp:function |
involved in allergic inflammation
mediates effects of IL-5 promotes eosinophil activation promotes eosinophil survival |
https://www.w3.org/2000/01/rdf-schema#label |
IL-5 receptor
|
gptkbp:location |
gptkb:cell_membrane
|
gptkbp:subunit |
gptkb:IL-5Rα
gptkb:common_beta_chain_(βc) |
gptkbp:target |
gptkb:benralizumab
gptkb:mepolizumab gptkb:reslizumab |
gptkbp:type |
gptkb:MAPK_pathway
gptkb:PI3K_pathway gptkb:JAK-STAT_pathway |
gptkbp:bfsParent |
gptkb:IL5
|
gptkbp:bfsLayer |
6
|