Cushing's syndrome

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkbp:affects adults
children
humans
gptkbp:alsoKnownAs hypercortisolism
gptkbp:causedBy adrenal tumor
pituitary adenoma
ectopic ACTH production
excess cortisol
prolonged corticosteroid use
gptkbp:complication gptkb:cardiovascular_disease
infections
bone fractures
psychiatric disorders
gptkbp:diagnosedBy gptkb:dexamethasone_suppression_test
24-hour urinary free cortisol
ACTH level measurement
late-night salivary cortisol
gptkbp:field endocrinology
gptkbp:firstDescribed 1932
gptkbp:gender more common in women
https://www.w3.org/2000/01/rdf-schema#label Cushing's syndrome
gptkbp:ICD-10_code E24
gptkbp:MeSH_ID D003480
gptkbp:namedAfter gptkb:Harvey_Cushing
gptkbp:prevalence rare
gptkbp:relatedTo gptkb:Cushing's_disease
Addison's disease
adrenal insufficiency
gptkbp:riskFactor long-term corticosteroid therapy
gptkbp:signature acne
thin skin
easy bruising
central obesity
gptkbp:symptom gptkb:depression
gptkb:bone
gptkb:diabetes_mellitus
hypertension
muscle weakness
weight gain
hirsutism
moon face
purple striae
buffalo hump
gptkbp:treatment gptkb:drug
surgery
radiation therapy
adrenalectomy
gptkbp:bfsParent gptkb:Nausea
gptkbp:bfsLayer 5