Statements (45)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:EPO
EPX eosinophil granule major basic protein 2 |
| gptkbp:associatedWith |
myeloperoxidase
lactoperoxidase |
| gptkbp:biologicalProcess |
peroxidase activity
|
| gptkbp:cellularComponent |
gptkb:cytoplasm
secretory granule |
| gptkbp:contains_cofactor |
hemoglobin
|
| gptkbp:discoveredBy |
1960s
|
| gptkbp:EC_number |
1.11.2.2
|
| gptkbp:expressedIn |
bone marrow
peripheral blood eosinophils |
| gptkbp:foundIn |
eosinophil granulocytes
|
| gptkbp:function |
catalyzes oxidation of halides and pseudohalides
|
| gptkbp:gene |
EPX
|
| https://www.w3.org/2000/01/rdf-schema#label |
eosinophil peroxidase
|
| gptkbp:involves |
immune response
|
| gptkbp:locatedOnChromosome |
gptkb:17q23
|
| gptkbp:molecularWeight |
~75 kDa
|
| gptkbp:organism |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:PDB |
1Q3E
|
| gptkbp:postTranslationalModification |
glycosylation
proteolytic processing |
| gptkbp:produces |
hypochlorous acid
hypobromous acid hypoiodous acid hypohalous acids hypothiocyanous acid |
| gptkbp:role |
asthma
allergic inflammation eosinophilic disorders |
| gptkbp:structure |
homodimer
|
| gptkbp:substrate |
hydrogen peroxide
iodide chloride bromide halide ions thiocyanate |
| gptkbp:UniProtID |
P11678
|
| gptkbp:bfsParent |
gptkb:eosinophils
gptkb:eosinophil |
| gptkbp:bfsLayer |
7
|