Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:activatedBy |
gptkb:FADD
gptkb:death-inducing_signaling_complex_(DISC) |
| gptkbp:alternativeName |
gptkb:FLICE
gptkb:MACH gptkb:Mch5 |
| gptkbp:associatedWith |
gptkb:autoimmune_lymphoproliferative_syndrome
gptkb:cancer |
| gptkbp:biologicalProcess |
cysteine-type endopeptidase activity
|
| gptkbp:cleavage |
gptkb:caspase_7
gptkb:Bid caspase 3 |
| gptkbp:discoveredIn |
1996
|
| gptkbp:EC_number |
3.4.22.61
|
| gptkbp:function |
apoptosis
inflammatory response |
| gptkbp:HGNC_ID |
1509
|
| https://www.w3.org/2000/01/rdf-schema#label |
caspase 8
|
| gptkbp:inhibitedBy |
gptkb:c-FLIP
|
| gptkbp:involvedIn |
extrinsic apoptotic signaling pathway
death receptor signaling pathway |
| gptkbp:locatedIn |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:locatedOnChromosome |
2q33-q34
|
| gptkbp:OMIM |
601763
|
| gptkbp:product |
gptkb:CASP8_gene
|
| gptkbp:UniProtID |
gptkb:Q14790
|
| gptkbp:bfsParent |
gptkb:CASP8
gptkb:E2F_transcription_factor_1 |
| gptkbp:bfsLayer |
8
|